SummarySkeletal muscle integrity is widely recognized in recent years to affect human holistic health. Glucose meta-bolic disorders, obesity, and muscle health are closely connected through a complex relationship, which remains incompletely understood. Therefore, this project addresses this critical gap and is expected to pro-vide valuable insights on the interplay of prediabetes/type 2 diabetes (T2D), sarcopenia/sarcopenic obesity (SO) and skeletal muscle mass and function, and the potential of future prevention of sarcopenia and SO, two conditions primarily affecting middle-aged and older adults, that are strongly related to muscle mass and function.

Keywords diabetes glucose-metabolism grip-strength magnetic-resonance-imaging muscle-quality muscle-quantity prediabetes sarcopenia sarcopenic-obesity

InstitutionsDeutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Institut für Epidemiologie, Universitätsmedizin Greifswald, Helmholtz Zentrum München, Universität Regensburg, Radiologie Freiburg, Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke, PhD Student at Ludwig-Maximilians university, Universitätsklinikum Tübingen, Universitätsmedizin Greifswald, Institut für Community Medicine, Abtlg. SHIP-KEF, Deutsches Diabetes-Zentrum