SummaryGlobally, higher tuberculosis (TB) associated mortality and case-fatality rates are consistently reported among males. Additionally, approximately twice as many men as women develop active TB, although, this disparity varies by region. These differences stems from factors such as variations in exposure and infection risk, immunological functions, other biological and social risk factors, and access to healthcare, which are partially understood. Depending on the context, these factors likely contribute to gender disparities in TB incidence and outcomes to varying degrees. In Germany, TB additionally, disproportionately affects various subgroups such as individuals with a migration background, reflecting persistent structural, regional (East/West), and social inequalities. Understanding these gender-specific mortality patterns and post-TB health trajectories is essential for adapting prevention, treatment, and follow-up programs in a gender-sensitive manner, as required by international guidelines. Our study aims to cross-sectionally assess mortality risks among individuals with a history of TB and comorbidities as well as how these risks vary by gender, migration status, and regional context , while also exploring its risk factors in a large, population-based sample. The duration of the project is expected to be 12 months.

Keywords Tuberkulose gender migration-background mortality

InstitutionsHelmholtz Centre for Infection Research, Universität Münster, Helmholtz Zentrum für Infektionsforschung, HZI, Helmholtz-Zentrum für Infektionsforschung