SummaryThe human body stores excess energy as adipose tissue, predominantly as subcutaneous and visceral adipose tissue, but also in the liver, pancreas, bone marrow, skeletal muscle, and ectopically around other organs like heart and kidney. Dietary macronutrient (carbohydrates, fat, protein) and alcohol intake directly impact energy balance and thus influence body weight maintenance. Since adipose tissue reflects excess energy storage, investigating habitual dietary intake can unveil potential mechanisms of fat accumulation and mobilization, which are central to body composition changes. Currently, it is unclear if overall energy, macronutrient intake, and dietary patterns influence specific adipose tissue depots differently from overall body weight. Thus, we aim to study the associations of habitual dietary intake with body composition at baseline and body composition changes during follow-up, derived from magnetic resonance imaging, including subcutaneous and visceral adipose tissue, and fat in liver, pancreas, bone marrow, skeletal muscle, heart and kidney.

Keywords MR-imaging body-composition habitual-diet

InstitutionsUniversitätsklinikum Freiburg, Lehrstuhl für Epidemiologie, Universtitätsklinikum Augsburg, Radiologie Freiburg, Universitätsklinikum Freiburg, Klinik für Diagnostische und Interventionelle Radiologie, Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke, Helmholtz Zentrum München