SummaryBoth, visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) are associated with cardiovascular disease (CVD) risk. VAT, in particular, is considered a relevant contributor to CVD risk due to its secretion of pro-inflammatory and vasoactive substances. The role of SAT remains controversial, with some studies reporting a positive but weaker association with CVD risk compared to VAT. As measurements of VAT or SAT alone do not adequately reflect fat distribution or total body fat mass, the VAT-to-SAT ratio has been proposed as an independent predictor of CVD and related risk factors. In this project, we would like to investigate associations of VAT, SAT, the VAT-to-SAT ratio with i) cardiometabolic risk factors and ii) self-reported CVD events and diabetes.

Keywords CVD SAT VAT cardiovascular-di subcutaneous-adipose-tissue visceral-adipose-tissue

InstitutionsUniversität Kiel, Universitätsklinikum Regensburg, Universität Regensburg