SummaryCOVID-19 emerged as a pandemic in late 2019 and led to 776.8 million infections and 7.074 million deaths worldwide. This enveloped virus primarily spreads through the respiratory tract and causes various symptoms, with severe cases more common in the elderly and those with underlying health conditions. Normal immune response needs a lot of energy that can be generated only through metabolism. Therefore, there is a need to determine the immune response after vaccination and infection in healthy as well those individuals with underlying conditions and abnormal metabolic functions. Therefore, details analyses of the data are needed to measure COVID-19 vaccines efficacy and association of the underlying conditions as well as those involved in body metabolism.

Keywords COVID-19 immunity infections liver metabolism thyroid underlying-health-conditions vaccine

InstitutionsUniversity Medizine Greifswald, HZI, Helmholtz Zentrum für Infektionsforschung, Universitätsmedizin Greifswald, Helmholtz-Zentrum für Infektionsforschung, University Medicine Greifswald, Martin-Luther-Universität Halle-Wittenberg, Universitätsmedizin Greifswald, Institut für Community Medicine, Abtlg. SHIP-KEF