Using directed brain connectivity with Multi-Modal Data from the NAKO Study and detect aging phenotypes

KeyNAKO-1048

Project leadMuthuraman Muthuraman

Approval date31.03.2025

Published date17.10.2025

SummaryAging is a complex biological process that significantly impacts various aspects of brain function and structure. Understanding the neural correlates of aging is essential for identifying early biomarkers of neurodegeneration and cognitive decline. By utilizing structural connectivity measures obtained from T1-weighted MRI and Diffusion Tensor Imaging (DTI), alongside directed functional connectivity assessed through functional MRI (fMRI), we can explore the complexities of brain aging in a robust manner.

Keywords Aging-Phenotypes Directed-connectivity structural-and-functional-connectivity

InstitutionsUniversity of Augsburg, Forschungszentrum Jülich

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